GPR40 agonist 4

• UNSPSC Description:

  GPR40 agonist 4 is a potent free fatty acid receptor 1 (FFA1/ GPR40) agonist with a pEC50 of 7.54.

• Target Antigen:

  Free Fatty Acid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/FAA1_agonist-1.html

• Purity:

  98.38

• Solubility:

  DMSO : 160 mg/mL (ultrasonic;warming)

• Smiles:

  ClC1=CC=CC=C1C2=CC(COC3=CC=C(S(CC(O)=O)(=O)=O)C=C3)=CC=C2

• Molecular Weight:

  416.87

• References & Citations:

  [1]Li Z, et al. Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes. Eur J Med Chem. 2017 Sep 29;138:458-479.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2102196-57-4