GPR40 agonist 1

• UNSPSC Description:

  GPR40 agonist 1 is a potent and novel GPR40 full agonist with an EC50 of 2 nM and 17 nM for hGPR40 and rGPR40, respectively.

• Target Antigen:

  Free Fatty Acid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/GPR40_agonist_1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=NC=C(F)C(C2=C(CC(C)C)N=C(COC3=CC=CC([C@H](C4CC4)CC(O)=O)=C3)C=N2)=C1

• Molecular Weight:

  479.54

• References & Citations:

  [1]Meegalla SK, et al. Discovery of a novel potent GPR40 full agonist. Bioorg Med Chem Lett. 2018 Feb 15;28(4):720-726.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1853982-41-8