GPR40 agonist 1

• Description :

  GPR40 agonist 1 is a potent and novel GPR40 full agonist with an EC50 of 2 nM and 17 nM for hGPR40 and rGPR40, respectively.

• CAS Number :

  [1853982-41-8]

• UNSPSC :

  12352005

• Target :

  Free Fatty Acid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/GPR40_agonist_1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=NC=C(F)C(C2=C(CC(C)C)N=C(COC3=CC=CC([C@H](C4CC4)CC(O)=O)=C3)C=N2)=C1

• Molecular Formula :

  C27H30FN3O4

• Molecular Weight :

  479.54

• References & Citations :

  [1]Meegalla SK, et al. Discovery of a novel potent GPR40 full agonist. Bioorg Med Chem Lett. 2018 Feb 15;28 (4) :720-726.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported