GPR40 agonist 1

CAT: 0804-HY-111359Size: 1 EachDry Ice: NoHazardous: No

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Description

GPR40 agonist 1 is a potent and novel GPR40 full agonist with an EC50 of 2 nM and 17 nM for hGPR40 and rGPR40, respectively.

CAS Number

1853982-41-8

UNSPSC

12352005

Target

Free Fatty Acid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/GPR40_agonist_1.html

Solubility

10 mM in DMSO

Smiles

COC1=NC=C(F)C(C2=C(CC(C)C)N=C(COC3=CC=CC([C@H](C4CC4)CC(O)=O)=C3)C=N2)=C1

Molecular Formula

C27H30FN3O4

Molecular Weight

479.54

References & Citations

[1]Meegalla SK, et al. Discovery of a novel potent GPR40 full agonist. Bioorg Med Chem Lett. 2018 Feb 15;28 (4) :720-726.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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