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GPR40 agonist 7

CAT: 0804-HY-162136Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162136Size:1 Each
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Description
GPR40 agonist 7 (Compound 1) is an orally active G protein-coupled receptor 40 (GPR40) agonist. GPR40 agonist 7 can significantly increase insulin and GLP-1 secretion, and has a hypoglycemic effect in vivo with an ED50 of 0.58 mg/kg[1]
CAS Number
1821647-46-4
UNSPSC
12352005
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gpr40-agonist-7.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(N2CC[C@@H](OC3=CC=C(N4[C@@H](CC(O)=O)[C@H](C)[C@@H](OCCCOC)C4)C=C3)[C@H](C)C2)C=C(OC)N=C1
Molecular Formula
C29H40ClN3O6
Molecular Weight
562.10
References & Citations
[1]Hou X, et al. Evolution of the Synthetic Process to an Advanced GPR40 Agonist[J]. Organic Process Research & Development, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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