NR-V04

CAT: 0804-HY-159779-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-159779-01Size:5 mg
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Description
NR-V04 is a PROTAC based NR4A1 degrader (Red: NR4A1 inhibitor (HY-13067), black: linker, Blue: E3 ligase ligand) [1].
CAS Number
[2766608-52-8]
UNSPSC
12352005
Target
Nuclear Hormone Receptor 4A/NR4A; PROTACs
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nr-v04.html
Purity
96.71
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@]([C@@]3([H])[C@@](CC1)(CC[C@](C)(C3)C(NCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@@H](C[C@H](C4)O)C(N[C@H](C5=CC=C(C6=C(N=CS6)C)C=C5)C)=O)=O)=O)=O)C)(CC[C@@]7(C2=CC=C8C7=CC(C(O)=C8C)=O)C)C
Molecular Formula
C62H87N5O11S
Molecular Weight
1110.45
References & Citations
[1]Weizhou ZHANG, et al. Modulators of nuclear receptor subfamily 4 group a member 1 (nr4a1) and uses thereof. US, WO2022072094. 2022-04-07.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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