NR-7h

CAT: 0931-T84895-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T84895-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2550399-06-7
Target
Others|||p38 MAPK|||PROTACs
Related Pathways
Others|||MAPK|||PROTAC
Bioactivity
NR-7h is a potent and selective degrader of p38? and p38?, exhibiting DC50 values of 24 nM for p38? in T47D cells and 27.2 nM in MB-MDA-231 cells, respectively [1].
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCNC(CCCN4C=C(CCCCNC(=O)C5=CC(=C(C)C=C5)N6C(=O)C(Br)=C(OCC7=C(F)C=C(F)C=C7)C=C6C)N=N4)=O
Molecular Formula
C48H50BrF2N9O8
Molecular Weight
998.87
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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