NR-7h

• Target :

  Others|||p38 MAPK|||PROTACs

• Related Pathways :

  Others|||MAPK|||PROTAC

• Bioactivity :

  NR-7h is a potent and selective degrader of p38? and p38?, exhibiting DC50 values of 24 nM for p38? in T47D cells and 27.2 nM in MB-MDA-231 cells, respectively [1].

• Smiles :

  O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCNC(CCCN4C=C(CCCCNC(=O)C5=CC(=C(C)C=C5)N6C(=O)C(Br)=C(OCC7=C(F)C=C(F)C=C7)C=C6C)N=N4)=O

• Molecular Formula :

  C48H50BrF2N9O8

• Molecular Weight :

  998.87

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2550399-06-7