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NR 7h

CAT: 0931-T36260Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T36260Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others
Related Pathways
Others
Bioactivity
Potent and selective p38α and p38β degrader (DC50 < 50 nM) . Displays no significant degradation of p38γ, p38δ, JNK1/2 or ERK1/2. Inhibits phosphorylation of MK2 in UV-treated cancer cells and LPS-stimulated bone marrow-derived macrophages (BMDM) . Exhibits similar effect to p38α gene knockout in BBL358 cells. Active in vivo.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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