RegisterLogin

PD 90780

CAT: 0804-HY-110166-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-110166-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PD 90780 is a non peptide antagonist of nerve growth factor (NGF) . PD 90780 interacts with NGF, prevents NGF binds with p75NTR. PD 90780 inhibits NGF-p75NTR interaction with IC50s of 23.1 and 1.8 μM in PC12 cells and PC12nnr5 cells, respectively[1] .
CAS Number
[77422-99-2]
UNSPSC
12352005
Target
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pd-90780.html
Purity
99.0
Solubility
DMSO : 31.25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CN1C2=CC(C(O)=O)=NN2C(C3=CC(NC(C4=CC=CC=C4)=O)=CC=C13)=O
Molecular Formula
C19H14N4O4
Molecular Weight
362.34
References & Citations
[1]Colquhoun A , et al. Differential activity of the nerve growth factor (NGF) antagonist PD90780 [7- (benzolylamino) -4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic acid] suggests altered NGF-p75NTR interactions in the presence of TrkA. J Pharmacol Exp Ther. 2004 Aug;310 (2) :505-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-144649PD-1/PD-L1-IN-24
HY-169190PD-1/PD-L1-IN-53
HY-144447PD-1/PD-L1-IN-17
HY-144746PD-1/PD-L1-IN-26
HY-175702PD-1/PD-L1-IN-57
HY-179180PD-1/PD-L1-IN-59
HY-145770PD-1/PD-L1-IN-19
HY-129172APD-1/PD-L1-IN 5
HY-168078PD-1/PD-L1-IN-50
HY-144442PD-1/PD-L1-IN-15

Alternative Products

CatalogName
462105-01PD 90780
A19821-5PD 90780 5mg
A19821-25PD 90780 25mg
A19821-1PD 90780 1mg
A19821-10PD 90780 10mg
A19821-50PD 90780 50mg
A19821-100PD 90780 100mg
A19821-10mM-DPD 90780 10mM * 1mL in DMSO
TR317702Pygopus 2 (PYGO2) Human shRNA Plasmid Kit (Locus ID 90780)
SR314035Pygopus 2 (PYGO2) Human siRNA Oligo Duplex (Locus ID 90780)

Popular Products