PD 90780

• Target:

  Others|||Trk receptor

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Others

• Purity:

  0.9922

• Bioactivity:

  PD 90780 is a non-peptide antagonist of nerve growth factor (NGF) that interacts with NGF and prevents it from binding to p75NTR, inhibiting the NGF-p75NTR interaction with IC50s of 23.1 and 1.8 µM in PC12 cells and PC12nnr5 cells, respectively.

• Smiles:

  Cn1c2cc(nn2c(=O)c2cc(NC(=O)c3ccccc3)ccc12)C(O)=O

• Molecular Formula:

  C19H14N4O4

• Molecular Weight:

  362.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  77422-99-2