PD 90780

• Target :

  Others|||Trk receptor

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Others

• Purity :

  0.9922

• Bioactivity :

  PD 90780 is a non-peptide antagonist of nerve growth factor (NGF) that interacts with NGF and prevents it from binding to p75NTR, inhibiting the NGF-p75NTR interaction with IC50s of 23.1 and 1.8 µM in PC12 cells and PC12nnr5 cells, respectively.

• Smiles :

  Cn1c2cc(nn2c(=O)c2cc(NC(=O)c3ccccc3)ccc12)C(O)=O

• Molecular Formula :

  C19H14N4O4

• Molecular Weight :

  362.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  77422-99-2