PD 90780

CAT: 0931-MF-0023244-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0023244-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
77422-99-2
Target
Others|||Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors|||Others
Purity
0.9922
Bioactivity
PD 90780 is a non-peptide antagonist of nerve growth factor (NGF) that interacts with NGF and prevents it from binding to p75NTR, inhibiting the NGF-p75NTR interaction with IC50s of 23.1 and 1.8 µM in PC12 cells and PC12nnr5 cells, respectively.
Smiles
Cn1c2cc(nn2c(=O)c2cc(NC(=O)c3ccccc3)ccc12)C(O)=O
Molecular Formula
C19H14N4O4
Molecular Weight
362.34
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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