4β-Hydroxycholesterol-d5

• Description :

  4β-Hydroxycholesterol-d5 is the deuterium labeled 4β-Hydroxycholesterol (HY-124265) . 4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation[1][2].

• UNSPSC :

  12352211

• Target :

  Endogenous Metabolite; Isotope-Labeled Compounds

• Type :

  Isotope-Labeled Compounds

• Related Pathways :

  Metabolic Enzyme/Protease; Others

• Field of Research :

  Metabolic Disease

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@](C([2H])([2H])C[C@]1(C2=C([2H])C[C@@]3([C@@]1(CC[C@]4([C@]3(CC[C@@]4([C@@H](CCCC(C)C)C)[H])[H])C)[H])[H])C)([2H])[C@]2([2H])O

• Molecular Formula :

  C27H41D5O2

• Molecular Weight :

  407.68

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Granchi C, et al. 4-Aryliden-2-methyloxazol-5 (4H) -one as a new scaffold for selective reversible MAGL inhibitors. J Enzyme Inhib Med Chem. 2016;31 (1) :137-46.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported