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4β-Hydroxycholesterol-d5

CAT: 0804-HY-124265S1-01Size: 5 mgDry Ice: NoHazardous: No
CAT#: HY-124265S1-01Size: 5 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4β-Hydroxycholesterol-d5 is the deuterium labeled 4β-Hydroxycholesterol (HY-124265) . 4β-hydroxy Cholesterol is a major oxysterol cholesterol metabolite and a precursor in the synthesis of bile acids that is found in human circulation[1][2].
UNSPSC
12352211
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
O[C@](C([2H])([2H])C[C@]1(C2=C([2H])C[C@@]3([C@@]1(CC[C@]4([C@]3(CC[C@@]4([C@@H](CCCC(C)C)C)[H])[H])C)[H])[H])C)([2H])[C@]2([2H])O
Molecular Formula
C27H41D5O2
Molecular Weight
407.68
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Granchi C, et al. 4-Aryliden-2-methyloxazol-5 (4H) -one as a new scaffold for selective reversible MAGL inhibitors. J Enzyme Inhib Med Chem. 2016;31 (1) :137-46.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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