MY-1442

CAT: 0804-HY-162089-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-162089-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

MY-1442 (I-3) is a microtubulin polymerization inhibitor. MY-875 inhibits tubulin polymerization by targeting colchicine binding sites. MY-1442 has anticancer activity. MY-1442 can induce apoptosis of MGC-803 cells and inhibit cell migration[1].

CAS Number

3050871-87-6

UNSPSC

12352005

Target

Apoptosis; Microtubule/Tubulin

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/my-1442.html

Purity

99.25

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

COC1=CC=C2N(C(C3=CC=CC=C3O4)=CC4=O)CCCC2=C1

Molecular Formula

C19H17NO3

Molecular Weight

307.34

References & Citations

[1]Tian XY, et al. Discovery of novel coumarin-based derivatives as inhibitors of tubulin polymerization targeting the colchicine binding site with potent anti-gastric cancer activities. Eur J Med Chem. 2023 Dec 22;265:116079.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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GTR19237090-01	MY-1B
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T78798-01	MY-673

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