MY-673

CAT: 0931-T78798-01Size: 25 mgDry Ice: NoHazardous: No

CAT#:0931-T78798-01Size:25 mg

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AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2944459-96-3

Target

Apoptosis|||Others|||ERK|||Microtubule Associated|||TGF-beta/Smad

Related Pathways

Cytoskeletal Signaling|||Stem Cells|||Apoptosis|||Others|||MAPK

Bioactivity

MY-673, a colchicine binding site inhibitor (CBSI), impedes tubulin polymerization and disrupts the ERK signaling pathway, consequently modulating SMAD4 protein expression in the TGF-?/SMAD pathway. This compound effectively reduces cell proliferation and migration while inducing apoptosis in both in vivo and in vitro settings [1].

Smiles

O=C1CN(C=2C(=CC(OC)=CC2)N1)C=3C=4C(OC(=O)C3)=CC=CC4

Molecular Formula

C18H14N2O4

Molecular Weight

322.31

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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