MY-673

• Target :

  Apoptosis|||Others|||ERK|||Microtubule Associated|||TGF-beta/Smad

• Related Pathways :

  Cytoskeletal Signaling|||Stem Cells|||Apoptosis|||Others|||MAPK

• Bioactivity :

  MY-673, a colchicine binding site inhibitor (CBSI), impedes tubulin polymerization and disrupts the ERK signaling pathway, consequently modulating SMAD4 protein expression in the TGF-?/SMAD pathway. This compound effectively reduces cell proliferation and migration while inducing apoptosis in both in vivo and in vitro settings [1].

• Smiles :

  O=C1CN(C=2C(=CC(OC)=CC2)N1)C=3C=4C(OC(=O)C3)=CC=CC4

• Molecular Formula :

  C18H14N2O4

• Molecular Weight :

  322.31

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2944459-96-3