Trk-C

CAT: 0209-101-M690Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-101-M690Size:100 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Members of the Tyrosine Kinase Receptor (Trk) family (TrkA, TrkB, and TrkC) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth. TrkC is predominantly expressed in the central nervous system.
Synonyms
NTRK3; TRKC; gp145 (trkC)
NCBI Gene ID
4916
UniProt
Q16288
Accession Number
NP_001012338
Accession Number mRNA
NM_001012338
Chromosomal Location
15q25
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Trk-C
Clone
(#9R22)
Applications
WB, IHC (F)
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

Related Products

CatalogName
101-M688Trk-A
103-M196Trk-B
101-M689Trk-B
101-M526Junctional adhesion molecule C (JAM-C)
100-412SGlu-C
104-PA10VEGF-C
101-M90VEGF-C
101-M204Activin-C
101-M89VEGF-C
101-MBi89VEGF-C

Alternative Products

CatalogName
338202-01Trk C
OM636562-01Trk C Antibody
sc-80403Trk C (WW6)
sc-517245Trk C (7H6)
346765-01Trk C discontinued
sc-514932Trk (C-8)
MBS2537200-01Trk C Polyclonal Antibody
MB67138-01TRK C monoclonal antibody
STJ98432Anti-Trk C antibody
250894Trk A/B/C Antibody

Popular Products