Trk-A

CAT: 0209-101-M688Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-101-M688Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TrkA, the product of the protooncogene trk, is a member of the neurotrophic tyrosine kinase receptor family that has three members. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a conserved complex subdomain organization consisting of a signal peptide, two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains in the extracellular region, as well as an intracellular region that contains the tyrosine kinase domain.
Synonyms
NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
NCBI Gene ID
4914
UniProt
P04629
Accession Number
NP_001012331
Accession Number mRNA
NM_001012331
Chromosomal Location
1q21-q22
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant Trk-A
Clone
(#8X5)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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