IP-10 (CXCL10) Recombinant Protein

IP-10 (CXCL10) Recombinant Protein

• Description: IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant rat IP-10 is an 8.6 kDa protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.
• Synonyms: gamma-Interferon inducible protein 10, CXCL10, crg-2
• CAS Number: 9000-83-3
• NCBI Gene ID: 245920
• UniProt: P48973
• Accession Number: NP_620789.1
• Accession Number mRNA: NM_139089.1
• Gene Location: 14p22
• Host: E. coli
• Origin Species: Rat
• Species Reactivity: Rat, Human
• Sequence: IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP
• Detection Range: Determined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 10.0-50.0 ng/ml.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 77
• Form: Lyophilized
• Molecular Weight: 8.6 kDa
• Shipping Conditions: Room Temperature