Rabbit Anti-Mouse IP-10 Polyclonal Antibody
CAT:
209-103-P21
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Rabbit Anti-Mouse IP-10 Polyclonal Antibody
- Description: Chemokine (C-X-C motif) ligand 10 (CXCL10) is a small cytokine belonging to the CXC chemokine family that is also known as 10 kDa interferon-gamma-induced protein (?-IP10 or IP-10). CXCL10 is secreted by several cell types in response to IFN-?. These cell types include monocytes, endothelial cells and fibroblasts. CXCL10 has been attributed to several roles, such as chemoattraction for monocytes and T cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. The gene for CXCL10 is located on human chromosome 4 in a cluster among several other CXC chemokines. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3. The three-dimensional crystal structure of this chemokine has been determined under 3 different conditions to a resolution of up to 1.92A. IP-10 Mouse Recombinant produced in E.Coli is a single,non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of 8701 Dalton.
- Synonyms: Cxcl10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
- CAS Number: 9007-83-4
- NCBI Gene ID: 15945
- UniProt: P17515
- Accession Number: NP_067249.1
- Accession Number mRNA: NM_021274.2
- Gene Location: 5 E2; 5 53.0 cM
- Host: Rabbit
- Origin Species: Mouse
- Species Reactivity: Mouse
- Target Antigen: Recombinant Mouse IP-10
- Clone: Rabbit IgG
- Validated Applications: ELISA, WB, N, IHC
- Purification Method: Antigen-affinity purified
- Form: Lyophilized from PBS
- Buffer: PBS
- Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
- Shipping Conditions: Room Temperature
- Storage Conditions: The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.