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IL-7R alpha EC

CAT: 0209-101-M509Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M509Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The biological effects of IL-7 are mediated by the binding of IL-7 to the specific cell surface receptor complex. The functional high-affinity IL-7 receptor (IL-7 R) comprises the IL-7 R alpha chain in association with the common gamma chain (gamma c) . Both IL-7 R alpha and gamma c are members of the hematopoietin receptor superfamily. Human and mouse IL-7 R alpha show 64% amino acid sequence identity. IL-7 R alpha transcripts were observed in murine spleen, thymus, fetal liver, developing T cells, B cells, mature T cells and bone marrow-derived macrophages.
Synonyms
IL7R; ILRA; CD127; IL7RA; CDW127; IL-7R-alpha
NCBI Gene ID
3575
UniProt
P16871
Accession Number
NP_002176.2
Accession Number mRNA
NM_002185.2
Chromosomal Location
5p13
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-7R alpha EC domain
Clone
(#10V5)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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