IL-7R alpha

• Description :

  The biological effects of IL-7 are mediated by the binding of IL-7 to the specific cell surface receptor complex. The functional high-affinity IL-7 receptor (IL-7 R) comprises the IL-7 R alpha chain in association with the common gamma chain (gamma c) . Both IL-7 R alpha and gamma c are members of the hematopoietin receptor superfamily. Human and mouse IL-7 R alpha show 64% amino acid sequence identity. IL-7 R alpha transcripts were observed in murine spleen, thymus, fetal liver, developing T cells, B cells, mature T cells and bone marrow-derived macrophages.

• Synonyms :

  Il7r; CD127; IL-7Ralpha

• NCBI Gene ID :

  16197

• UniProt :

  P16872

• Accession Number :

  NP_032398.3

• Accession Number mRNA :

  NM_008372.4

• Chromosomal Location :

  15 A1; 15 4.6 cM

• Reactivity :

  Anti-Mouse

• Cross Reactivity :

  Mouse

• Target Antigen :

  Recombinant mouse protein of IL-7alpha

• Clone :

  (#6F11)

• Applications :

  WB

• Purification Method :

  Protein G/A chromatography

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source :

  Rat

• Isotype :

  IgG2