IL-2 receptor beta

• Description:

  IL-2 Receptor beta in frozen human lymph node. View IL-2 R beta IHC images. IL-2 R beta is a 551 amino acid (aa) precursor type I membrane protein with a 26 aa signal peptide, a 214 aa extracellular region, a 25 aa transmembrane region and a 286 aa cytoplasmic domain. IL-2 R beta binds IL-2 as a part of the IL-2 R alpha/IL-2 R beta/common gamma chain complex.

• Synonyms:

  FASLG; FASL; CD178; CD95L; CD95-L; TNFSF6; APT1LG1

• NCBI Gene ID:

  3560

• UniProt:

  P14784

• Accession Number:

  NP_000869.1

• Accession Number mRNA:

  NM_000878.3

• Chromosomal Location:

  22q13; 22q13.1

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human IL-2 R beta EC domain

• Clone:

  (#1Y60)

• Applications:

  IHC (P), N

• Purification Method:

  Protein G chromatography

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  PBS

• Storage Conditions:

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source:

  Mouse

• Isotype:

  IgG1