IL-2 receptor alpha

• Description :

  IL2-Ra is one of the three constituent subunits of the IL2 receptor. IL-2Ra is released into the serum after increased cellular expression such as increased activation of B and T cells. Clinical manifestations of IL2-Ra elevation include autoimmune conditions and some leukemias and lymphomas. Interleukin-2R Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (22-213) corresponding to the mature IL2-R protein with an amino terminal hexahistidine tag. The IL-2R is purified by proprietary chromatographic techniques.

• Synonyms :

  IL2RA; CD25; IL2R; TCGFR; IDDM10

• NCBI Gene ID :

  3559

• UniProt :

  P01589

• Accession Number :

  NP_000408.1

• Accession Number mRNA :

  NM_000417.2

• Chromosomal Location :

  10p15-p14

• Reactivity :

  Anti-Human

• Cross Reactivity :

  Human

• Target Antigen :

  Recombinant human IL-2 R alpha EC domain

• Clone :

  (#1X27)

• Applications :

  WB, IHC (P), N

• Purification Method :

  Protein G chromatography

• Assay Protocol :

  Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.

• Form :

  Lyophilized

• Buffer :

  PBS

• Reconstitution :

  PBS

• Storage Conditions :

  Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.

• Host or Source :

  Mouse

• Isotype :

  IgG1