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IL-18 receptor beta

CAT: 0209-101-M494Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M494Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The functional IL-18 receptor complex is composed of two subunits designated IL-18 R alpha (also termed IL-1 R5 and IL-1 Rrp) and IL-18 R beta (also termed IL-1 R7 and AcPL) . Both IL-18 R alpha and IL-18 R beta belong to the IL-1 receptor family. Although IL-18 R alpha by itself binds IL-18 with low-affinity and IL-18 R beta does not bind IL-18 in vitro, co-expression of IL-18 R alpha and IL-18 R beta is required for high-affinity binding and IL-18 responsiveness. IL-18 R is widely expressed in numerous tissues including spleen, thymus, leukocyte, liver, lung, heart, small and large intestine, prostate and placenta. It is not expressed in brain, skeletal muscle, kidney and pancreas.
Synonyms
IL18RAP; ACPL; CD218b; IL18RB; CDw218b
NCBI Gene ID
8807
UniProt
O95256
Accession Number
NP_003844.1
Accession Number mRNA
NM_003853.2
Chromosomal Location
2q12
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-18 R alpha EC domain
Clone
(#10D34)
Applications
WB, N
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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128418IL18RAP (Interleukin-18 Receptor Accessory Protein, IL-18 Receptor Accessory Protein, IL-18RAcP, Accessory Protein-like, AcPL, CD218 Antigen-like Family Member B, CDw218b, IL-1R Accessory Protein-like, IL-1RAcPL, Interleukin-1 Receptor 7, IL-1R-7, IL-1R7, Interleukin-18 Receptor Accessory Protein-like, Interleukin-18 Receptor beta, IL-18R-beta, IL-18Rbeta, CD218b, IL1R7, MGC120589, MGC120590)
I8440-03R-PEIL18RAP, NT (CD218b, CDw218b, CD218 Antigen-like Family Member B, Interleukin-1 Receptor 7, IL-1R-7, IL-1R7, Accessory Protein-like, AcPL, IL-1R Accessory Protein-like, IL-1RAcPL, Interleukin-18 Receptor beta, IL-18R-beta, IL-18Rbeta, Interleukin-18 Receptor Accessory Protein-like, Interleukin-18 Receptor Accessory Protein, IL-18 Receptor Accessory Protein, IL-18RAcP, IL1R7) (PE)
I8440-03RIL18RAP, NT (CD218b, CDw218b, CD218 Antigen-like Family Member B, Interleukin-1 Receptor 7, IL-1R-7, IL-1R7, Accessory Protein-like, AcPL, IL-1R Accessory Protein-like, IL-1RAcPL, Interleukin-18 Receptor beta, IL-18R-beta, IL-18Rbeta, Interleukin-18 Receptor Accessory Protein-like, Interleukin-18 Receptor Accessory Protein, IL-18 Receptor Accessory Protein, IL-18RAcP, IL1R7)
216616IL-3 Receptor beta (IL3R beta)

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