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IL-3 receptor beta

CAT: 0209-103-M253Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M253Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The high-affinity receptors for Interleukin-3 (IL-3), IL-5, and Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF) consist of a cytokine-specific a chain, and a shared common beta chain subunit (CD131) that is essential for receptor signaling. CD131 also associates with the receptor for Erythropoietin, forming a tissue-protective heteroreceptor complex. Phosphorylation of CD131 following receptor activation imparts growth and survival signals to the responding hematopoietic cells.
Synonyms
Csf2rb2; Bil3; Il3r; AIC2A; Il3rb; Il3rb2; BetaIl3; Csfgmrb
NCBI Gene ID
12984
UniProt
P26954
Accession Number
NP_031807.1
Accession Number mRNA
NM_007781.2
Chromosomal Location
15 E1; 15 43.3 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse protein of IL-3R beta extracellular domain
Clone
(#42A7)
Applications
WB
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG1

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Alternative Products

CatalogName
216616IL-3 Receptor beta (IL3R beta)
216709Interleukin 3 Receptor beta (IL-3Rb)
MBS618559-01IL-3, IL-5, GM-CSF Receptor, beta-common (bc)
mAP-0112Rat Monoclonal anti-mouse IL-3 Receptor beta
216245CD122 (Interleukin 2 Receptor beta, IL-2 Receptor beta)
130754OSMR (Oncostatin-M-specific Receptor Subunit beta, Interleukin-31 Receptor Subunit beta, IL-31 Receptor Subunit beta, IL-31R Subunit beta, IL-31R-beta, IL-31RB, OSMRB)
216731Interleukin-18 Receptor beta (IL-18R beta)
130755-BiotinOSMR (Oncostatin-M-specific Receptor Subunit beta, Interleukin-31 Receptor Subunit beta, IL-31 Receptor Subunit beta, IL-31R Subunit beta, IL-31R-beta, IL-31RB, OSMRB) (Biotin)
130754-PEOSMR (Oncostatin-M-specific Receptor Subunit beta, Interleukin-31 Receptor Subunit beta, IL-31 Receptor Subunit beta, IL-31R Subunit beta, IL-31R-beta, IL-31RB, OSMRB) (PE)
130755-APCOSMR (Oncostatin-M-specific Receptor Subunit beta, Interleukin-31 Receptor Subunit beta, IL-31 Receptor Subunit beta, IL-31R Subunit beta, IL-31R-beta, IL-31RB, OSMRB) (APC)

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