IL-4 receptor alpha

CAT: 0209-103-M254Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-103-M254Size:100 µg
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Description
Two types of IL-4 receptor complexes have been described. The typeI IL-4 receptor complex is composed of a high-affinity IL-4-binding subunit (referred to as IL-4 R or IL-4 R alpha) and the common gamma chain that does not bind IL-4 by itself. The type II IL-4 receptor complex is composed of IL-4 R and IL-13 R alpha 1. Besides IL-4 signals, the type II IL-4 receptor complex can also transduce IL-13 signals. In the type II complex, IL-4 R subunit binds only IL-4 and not IL-13. Similarly, the IL-13 R alpha 1 subunit binds only IL-13 and not IL-4.
Synonyms
Il4ra; Il4r; CD124
NCBI Gene ID
16190
UniProt
P16382
Accession Number
NP_001008700.1
Accession Number mRNA
NM_001008700.3
Chromosomal Location
7 F3; 7 62.0 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Recombinant mouse protein of the extracellular domain of IL-4 R
Clone
(#16F23)
Applications
WB
Purification Method
Protein G/A chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Rat
Isotype
IgG2

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CatalogName
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A136014Altrakincept Biosimilar (, Fusion - [IL4R (Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA) ])
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128471-APCIL4R (Interleukin-4 Receptor Subunit alpha, IL-4 Receptor Subunit alpha, IL-4R Subunit alpha, IL-4R-alpha, IL-4RA, CD124, IL4RA, 582J2.1, Soluble Interleukin-4 Receptor Subunit alpha, Soluble IL-4 Receptor Subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding Protein, IL4-BP) (APC)

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