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IL-10 receptor alpha

CAT: 0209-103-M242Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-103-M242Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Human and mouse IL-10 receptors are structurally related to the IFN-gamma receptor. These receptors are members of the class II subgroup of the cytokine receptor superfamily. The deduced amino acid sequence of human IL-10 R is approximately 60% identical to mouse IL-10 R. Although human IL-10 has cross-species activities and is active on mouse cells, mouse IL-10 is species-specific in its actions and does not bind to the human IL-10 receptor. The human IL-10 R gene has been mapped to chromosome 11q23.3. Recombinant IL-10 soluble receptor, consisting of the extracellular domain of IL-10 R, binds IL-10 with high affinity in solution and is a potent IL-10 antagonist.
Synonyms
Il10ra; Il10r; CDw210; CDw210a; mIL-10R; AW553859
NCBI Gene ID
16154
UniProt
Q61727
Accession Number
NP_032374.1
Accession Number mRNA
NM_008348.2
Chromosomal Location
9 A5.2; 9 26.0 cM
Reactivity
Anti-Mouse
Cross Reactivity
Mouse
Target Antigen
Mouse recombinant EC domain of IL-10R
Clone
(#9E12)
Applications
WB, IHC (P)
Purification Method
Protein A/G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Hamster
Isotype
IgG

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