IL-10 receptor alpha

CAT: 0209-101-M472Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M472Size:50 µg
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Description
Human and mouse IL-10 receptors are structurally related to the IFN-gamma receptor. These receptors are members of the class II subgroup of the cytokine receptor superfamily. The deduced amino acid sequence of human IL-10 R is approximately 60% identical to mouse IL-10 R. Although human IL-10 has cross-species activities and is active on mouse cells, mouse IL-10 is species-specific in its actions and does not bind to the human IL-10 receptor. The human IL-10 R gene has been mapped to chromosome 11q23.3. Recombinant IL-10 soluble receptor, consisting of the extracellular domain of IL-10 R, binds IL-10 with high affinity in solution and is a potent IL-10 antagonist.
Synonyms
IL10RA; CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1
NCBI Gene ID
3587
UniProt
Q13651
Accession Number
NP_001549.1
Accession Number mRNA
NM_001558.3
Chromosomal Location
11q23
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human IL-10 Rbalpha EC domain
Clone
(#7Q35)
Applications
WB
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG2

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