IFN beta

CAT: 0209-101-M772Size: 50 µgDry Ice: NoHazardous: No
CAT#:0209-101-M772Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFN-α is an acid-stable molecule that signals through IFN-α/βR, which is also used by IFN-β. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFN-α contains four highly conserved cysteine residues that form two disulfide bonds, one of which is necessary for biological activity. Recombinant Human IFN-β is a 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFN-β has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry.
Synonyms
Fibroblast Interferon, IFNB1, Type I Interferon
NCBI Gene ID
3456
UniProt
P01574
Accession Number
NP_002167.1
Accession Number mRNA
NM_002176
Chromosomal Location
9p21
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Human recombinant IFNbeta
Clone
(#7K51)
Applications
WB, N/B, IHC (F)
Purification Method
Protein G chromatography
Assay Protocol
Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
PBS
Storage Conditions
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20 °C for at least for six months without detectable loss of activity.
Host or Source
Mouse
Isotype
IgG1

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