RELM beta

CAT: 0209-M10-082Size: 25 µgDry Ice: NoHazardous: No

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CAT#:0209-M10-082Size:25 µg

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Description

RELMβ (Resistin-like molecule β/FIZZ2) is an 18 kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELMβ, and its molecular targets, are not fully known but, it has been suggested that it plays a regulatory role during inflammation and may also act to establish links among adipose tissue, the intestine and the liver (Rajala, M. et al. J. Clin. Invest. Vol. 111, 225-230 (2003) ) . Interestingly the molecular structure of RELMβ is highly homologous to that of the adipose-derived cytokine Resistin and RELMβ. These proteins share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Recombinant Murine RELMβ is an 18.0 kDa, consisting of two 83 amino acid residue chains.

Synonyms

Retnlb; Xcp3; Fizz2; Relmb; RELMbeta; 9030012B21Rik

NCBI Gene ID

57263

UniProt

Q99P86

Accession Number

NP_076370

Accession Number mRNA

NM_023881

Chromosomal Location

16 B5; 16 33.0 cM

Reactivity

Mouse

Cross Reactivity

Mouse, Pig, Intestinal Worm, Parasite

Sequence

MQCSFESLVD QRIKEALSRQ EPKTISCTSV TSSGRLASCP AGMVVTGCAC GYGCGSWDIR NGNTCHCQCS VMDWASARCC RMA

Endotoxin

< 0.1 ng/µg of protein (< 1EU/µg)

Purity

> 98% by SDS-PAGE & HPLC analyses

Bioactivity

Data not available.

Length

Form

Lyophilized

Molecular Weight

18 kDa

Host or Source

E. coli

UniProtKB · Q99P86

Resistin-like beta

RETNB_MOUSE · Mus musculus

View on UniProt ↗

Primary accession: Q99P86
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: Retnlb
Protein existence: 1: Evidence at protein level
Organism: Mus musculus (Mouse)
Taxonomy ID: 10090
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: Q9D286

Protein keywords

Technical term

3D-structureReference proteome

PTM

Disulfide bond

Molecular function

Hormone

Cellular component

Secreted

Domain

Signal

Related Products

Catalog	Name
M10-081-L250	RELM alpha
M10-053S	RELM gamma
M10-053-L500	RELM gamma
M10-053-L250	RELM gamma
M10-081-L100	RELM alpha
103-P80	RELM alpha
M10-081S	RELM alpha
M10-081	RELM alpha
M10-053-L1000	RELM gamma
M10-053-L100	RELM gamma

Alternative Products

Catalog	Name
MBS612785-01	RELM-beta (Resistin-Like Molecule-beta)(RELM-beta, FIZZ2, RELM-alpha, FIZZ1)
R1587-21A	RELM-beta (Resistin-Like Molecule-beta) (RELM-beta, FIZZ2, RELM-alpha, FIZZ1)
70R-RR006	RELM beta antibody
5654-30T	RELM-beta Antibody
MBS538189-01	RELM beta protein
600212	Mouse Relm beta
DF13943-BP	RELM beta Peptide
AK9085-0100	rHu RELM-beta
OPSD00086-5UG	Recombinant RELM-beta
MBS691595-01	Human RELM beta