GMF-beta

• Description:

  GMF-β a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines. Recombinant human GMF-β is a 16.5 kDa globular protein containing 141 amino acid residues including one intramolecular disulfide bond.

• Synonyms:

  GMFB; GMF

• NCBI Gene ID:

  2764

• UniProt:

  P60983

• Accession Number:

  NP_004115.1

• Accession Number mRNA:

  NM_004124

• Chromosomal Location:

  14q22.2

• Reactivity:

  Human

• Cross Reactivity:

  Human

• Sequence:

  SESLVVCDVA EDLVEKLRKF RFRKETNNAA IIMKIDKDKR LVVLDEELEG ISPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Data not available.

• Length:

  141

• Form:

  Lyophilized

• Molecular Weight:

  16.5 kDa

• Host or Source:

  E. coli