G-CSF Recombinant Protein

G-CSF Recombinant Protein

• Description: G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Recombinant rat G-CSF is a 21.6 kDa protein consisting of 196 amino acid residues.
• Synonyms: Granulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSFß, pluripoietin
• CAS Number: 9000-83-3
• NCBI Gene ID: 25610
• UniProt: P97712
• Accession Number: NP_058800.1
• Accession Number mRNA: NM_017104.1
• Gene Location: 10q31
• Host: E. coli
• Origin Species: rat
• Species Reactivity: Rat
• Sequence: MKKIPLLTVS SLPPSLPLPR SFLLKSLEQV RKIQARNTEL LEQLCATYKL CHPEELVLFG HSLGIPKASL SSCSSQALQQ TKCLSQLHSG LFLYQGLLQA LAGISSELAP TLDMLHLDVD NFATTIWQQM ESLGVAPTVQ PTQSTMPIFT SAFQRRAGGV LVTSYLQSFL ETAHHALHHL PRPAQKHFPE SLFISI
• Detection Range: Determined by its ability to stimulate the proliferation of mouse NFS-60 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 196
• Form: Lyophilized
• Molecular Weight: 21.6 kDa
• Shipping Conditions: Room Temperature