G-CSF Recombinant Protein

G-CSF Recombinant Protein

• Description: G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and mouse G-CSF are cross-species reactive. Recombinant murine G-CSF is a 19.0 kDa protein consisting of 179 amino acid residues.
• Synonyms: Csf3; Csfg; G-CSF; MGI-IG
• CAS Number: 9000-83-3
• NCBI Gene ID: 12985
• UniProt: P09920
• Accession Number: NP_034101.1
• Accession Number mRNA: NM_009971
• Gene Location: 11 D; 11 57.0 cM
• Host: E. coli
• Origin Species: Mouse
• Species Reactivity: Mouse, Rat
• Sequence: MVPLVTVSAL PPSLPLPRSF LLKSLEQVRK IQASGSVLLE QLCATYKLCH PEELVLLGHS LGIPKASLSG CSSQALQQTQ CLSQLHSGLC LYQGLLQALS GISPALAPTL DLLQLDVANF ATTIWQQMEN LGVAPTVQPT QSAMPAFTSA FQRRAGGVLA ISYLQGFLET ARLALHHLA
• Detection Range: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is ≤  0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 179
• Form: Lyophilized
• Molecular Weight: 19.0 kDa
• Shipping Conditions: Room Temperature