G-CSF Recombinant Protein

• Background:

  Human Granulocyte-Colony-Stimulating Factor (G-CSF) is 20 kD glycoprotein containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and it functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, Interleukin-1, and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF. In epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by Interleukin-17.

• NCBI Gene ID:

  1440

• Swiss Prot:

  P09919-2

• Accession Number:

  P09919-2

• Tag:

  Tag Free

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Immunology, Signal Transduction

• Buffer:

  Lyophilized from a 0.2 um filtered solution of 10mM HAc-NaAc, 150mM NaCl, 0.004% Tween 80, 5% Mannitol, pH 4.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

• Shipping Conditions:

  Room Temp

• Calculated Molecular Weight:

  18.8 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  Colony stimulating factor 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Granulocyte Colony-Stimulating Factor, G-CSF, Pluripoietin, Filgrastim, Lenograstim, CSF3, C17orf33, GCSF

• Species:

  Human

• Protein ID:

  117564

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3