G-CSF (Animal Free) Recombinant Protein

G-CSF (Animal Free) Recombinant Protein

• Description: G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant Human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.
• Synonyms: CSF3; GCSF; CSF3OS; C17orf33
• CAS Number: 9000-83-3
• NCBI Gene ID: 1440
• UniProt: P09919
• Accession Number: NP_000750.1
• Accession Number mRNA: NM_000759
• Gene Location: 17q11.2-q12
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Human, Mouse, Plant
• Sequence: TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
• Detection Range: Determined by its ability to stimulate the proliferation of mouse NFS-60 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
• Endotoxin: < 0.01 ng/ug of protein (< 0.1 EU/ug)
• Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
• Length: 174
• Form: Lyophilized
• Molecular Weight: 18.7 kDa
• Shipping Conditions: Room Temperature