G-CSF Recombinant Protein

G-CSF Recombinant Protein

• Description: G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and mouse G-CSF are cross-species reactive. Recombinant human G-CSF is an 18.7 kDa protein consisting of 174 amino acid residues.
• Synonyms: CSF3; GCSF; CSF3OS; C17orf33
• CAS Number: 9000-83-3
• NCBI Gene ID: 1440
• UniProt: P09919
• Accession Number: NP_000750.1
• Accession Number mRNA: NM_000759
• Gene Location: 17q11.2-q12
• Host: E. coli
• Origin Species: Human
• Species Reactivity: Monkey, Mouse, Pig, Human, Plant
• Sequence: TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEELVLL GHSLGIPWAP LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
• Detection Range: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
• Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
• Purity: > 98% by SDS-PAGE & HPLC analyses
• Length: 174
• Form: Lyophilized
• Molecular Weight: 18.7 kDa
• Shipping Conditions: Room Temperature