CEACAM-1 (dN)

• Description:

  Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, CEACAM-1 forms non-covalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice of CEACAM-1 variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.

• Synonyms:

  CEACAM1; BGP; BGP1; BGPI, CD66a

• NCBI Gene ID:

  634

• UniProt:

  P13688

• Accession Number:

  NP_001192273.1

• Accession Number mRNA:

  NM_001205344

• Chromosomal Location:

  19q13.2

• Reactivity:

  Anti-Human

• Cross Reactivity:

  Human

• Target Antigen:

  Recombinant human sCEA-1 (ΔN)

• Clone:

  Rabbit IgG

• Applications:

  E, WB, FC

• Purification Method:

  Protein A purified

• Assay Protocol:

  Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.

• Bioactivity:

  Western Blot: Use 2-5 µg/ml

• Form:

  Lyophilized

• Buffer:

  PBS

• Reconstitution:

  Water

• Storage Conditions:

  The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

• Host or Source:

  Rabbit