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CEACAM-1

CAT: 0209-101-M182Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0209-101-M182Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Carcinoembryonic Antigen-related Cell Adhesion Molecule 1 (CEACAM-1), also known as CD66a and BGP-I, is a 115 kDa type I transmembrane glycoprotein that belongs to the membrane-bound CEA subfamily of the CEA superfamily. On the surface of cells, it forms noncovalent homo- and heterodimers. The extracellular region contains three C2-type Ig-like domains and one N-terminal V-type Ig-like domain. Multiple splice variants involving regions C-terminal to the second C2-type domain (aa 320 and beyond) exist.
Synonyms
CEACAM1; BGP; BGP1; BGPI, CD66a
NCBI Gene ID
634
UniProt
P13688
Accession Number
NP_001192273.1
Accession Number mRNA
NM_001205344.1
Chromosomal Location
19q13.2
Reactivity
Anti-Human
Cross Reactivity
Human
Target Antigen
Recombinant human soluble CEACAM-1-Fc (produced in HEK293 cells)
Clone
(#B3)
Applications
WB, IHC, E, IF, IP, FC
Purification Method
Protein G chromatography
Assay Protocol
Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Bioactivity
ELISA: Use at 10 µg/ml; WB: Use at 5 µg/ml; Immunohistochemistry: Use at 10 µg/ml; FACS analysis: Use at 10 µg/ml.
Form
Lyophilized
Buffer
PBS
Reconstitution
Water
Storage Conditions
The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Notes
Anti-human CEACAM-1 (B3) interacts solely with human CEACAM-1 and shows no cross-reactivity with other CEACAMs expressed in human or other species!
Host or Source
Mouse
Isotype
IgG1, kappa

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