DN-108

• Target :

  PPAR

• Related Pathways :

  DNA Damage/DNA Repair|||Metabolism

• Bioactivity :

  DN-108, a thiazolidinedione derivative, acts as an orally active peroxisome proliferator-activated receptor ? (PPAR?) agonist with antidiabetic properties. It improves hyperglycemia, hypertriglyceridemia, and hyperinsulinemia in diabetic mouse models. DN-108 enhances tissue glucose uptake (e.g., increases 2-deoxyglucose uptake in L6 muscle cells) and inhibits fatty acid synthase activity, making it a promising candidate for type 2 diabetes research.

• Smiles :

  O=C1SC(C(=O)N1)CC2=CC=C(C=C2)NC(=O)C3(C=4C=CC=CC4)CC3

• Molecular Formula :

  C20H18N2O3S

• Molecular Weight :

  366.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  195604-21-8