SC-560

CAT: 0804-HY-59105-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-59105-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
SC-560 is a potent and selective COX-1 inhibitor with an IC50 of 9 nM.
CAS Number
[188817-13-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SC-560.html
Concentration
10mM
Purity
99.79
Solubility
DMSO : ≥ 100 mg/mL
Smiles
FC(C1=NN(C2=CC=C(OC)C=C2)C(C3=CC=C(Cl)C=C3)=C1)(F)F
Molecular Formula
C17H12ClF3N2O
Molecular Weight
352.74
Precautions
H302, H315, H319, H335
References & Citations
[1]Smith CJ, et al. Pharmacological analysis of cyclooxygenase-1 in inflammation. Proc Natl Acad Sci U S A. 1998 Oct 27;95 (22) :13313-8.|[2]Lampiasi N, et al. The selective cyclooxygenase-1 inhibitor SC-560 suppresses cell proliferation and induces apoptosis in human hepatocellular carcinoma cells. Int J Mol Med. 2006 Feb;17 (2) :245-52.|[3]Teng XW, et al. Formulation dependent pharmacokinetics, bioavailability and renal toxicity of a selective cyclooxygenase-1 inhibitor SC-560 in the rat. J Pharm Pharm Sci. 2003 May-Aug;6 (2) :205-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-1; COX-2

Related Products

CatalogName
HY-18016CGI 560
HY-149776RGH-560
HY-14174-01MRK-560
HY-W953595CRBN ligand-560
HY-19080SC-45662
HY-171099SC-919
HY-16451SC-49483
HY-14237SC-77964
HY-102065-01SC-19220
HY-19500-01SC-75416

Alternative Products

CatalogName
MBS3607393-01SC-560
B6786-25SC 560
A13023-2SC 560 2mg
A13023-10SC 560 10mg
A13023-25SC 560 25mg
A13023-50SC 560 50mg
A13023-5SC 560 5mg
A13023-100SC 560 100mg
A13023-10mM-DSC 560 10mM * 1mL in DMSO
TBI2531-5MGSC-560, Selective COX-1 inhibitor

Popular Products