CGI 560

• Description:

  CGI 560 is an inhibitor for Bruton's tyrosine kinase (BTK) with an IC50 of 400 nM.

• UNSPSC:

  12352005

• Target:

  Btk

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cgi-560.html

• Smiles:

  O=C(C1=CC=C(C(C)(C)C)C=C1)NC2=CC(C3=CN4C(C(NC5=CC=CC=C5)=N3)=NC=C4)=CC=C2

• Molecular Formula:

  C29H27N5O

• Molecular Weight:

  461.56

• References & Citations:

  [1]Lv J, et al., Development of Bruton's Tyrosine Kinase Inhibitors for Rheumatoid Arthritis. Curr Med Chem. 2018;25 (42) :5847-5859.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [845269-74-1]