CGI 560

• Description :

  CGI 560 is an inhibitor for Bruton's tyrosine kinase (BTK) with an IC50 of 400 nM.

• UNSPSC :

  12352005

• Target :

  Btk

• Type :

  Reference compound

• Related Pathways :

  Protein Tyrosine Kinase/RTK

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/cgi-560.html

• Smiles :

  O=C(C1=CC=C(C(C)(C)C)C=C1)NC2=CC(C3=CN4C(C(NC5=CC=CC=C5)=N3)=NC=C4)=CC=C2

• Molecular Formula :

  C29H27N5O

• Molecular Weight :

  461.56

• References & Citations :

  [1]Lv J, et al., Development of Bruton's Tyrosine Kinase Inhibitors for Rheumatoid Arthritis. Curr Med Chem. 2018;25 (42) :5847-5859.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [845269-74-1]