MRTF-A-IN-1

MRTF-A-IN-1

• UNSPSC Description: MRTF-A-in-1 (Compound 14) is MRTF-A inhibitor. MRTF-A-in-1 can inhibit cell proliferation and induce HCC cell aging[1].
• Target Antigen: Ras
• Type: Reference compound
• Related Pathways: GPCR/G Protein;MAPK/ERK Pathway
• Field of Research: Metabolic Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/mrtf-a-in-1.html
• Smiles: CC(C1=CC=C(C2=CC=CC(NC3=NC4=C(C=CC=C4)N3)=C2)C=C1)C
• Molecular Weight: 327.42
• References & Citations: [1]Franz MJ, et al. Identification of novel inhibitors of the transcriptional coactivator MRTF-A for HCC therapy. Mol Ther Oncol. 2024 Aug 6;32(3):200855.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported