MRTF-A-IN-2

MRTF-A-IN-2

• UNSPSC Description: MRTF-A-in-2 (Compound 16) is MRTF-A inhibitor. MRTF-A-in-1 can inhibit cell proliferation and induce HCC cell aging[1].
• Target Antigen: Ras
• Type: Reference compound
• Related Pathways: GPCR/G Protein;MAPK/ERK Pathway
• Field of Research: Metabolic Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/mrtf-a-in-2.html
• Smiles: FC1=CC(C2=CC=CC(NC3=NC4=C(C=CC=C4)N3)=C2)=CC=C1
• Molecular Weight: 303.33
• References & Citations: [1]Franz MJ, et al. Identification of novel inhibitors of the transcriptional coactivator MRTF-A for HCC therapy. Mol Ther Oncol. 2024 Aug 6;32(3):200855. https://pubmed.ncbi.nlm.nih.gov/39262570/
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported