MRTF-A-IN-2

• Description:

  MRTF-A-in-2 (Compound 16) is MRTF-A inhibitor. MRTF-A-in-1 can inhibit cell proliferation and induce HCC cell aging[1].

• UNSPSC:

  12352101

• Target:

  Ras

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; MAPK/ERK Pathway

• Field of Research:

  Metabolic Disease; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/mrtf-a-in-2.html

• Smiles:

  FC1=CC(C2=CC=CC(NC3=NC4=C(C=CC=C4)N3)=C2)=CC=C1

• Molecular Formula:

  C19H14FN3

• Molecular Weight:

  303.33

• References & Citations:

  [1]Franz MJ, et al. Identification of novel inhibitors of the transcriptional coactivator MRTF-A for HCC therapy. Mol Ther Oncol. 2024 Aug 6;32 (3) :200855. https://pubmed.ncbi.nlm.nih.gov/39262570/

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported