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Oltipraz (GMP)

CAT: 0804-HY-12519GSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12519GSize:1 Each
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Description
Oltipraz (GMP) is Oltipraz produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Oltipraz has an inhibitory effect on HIF-1α activation. Oltipraz is a potent Nrf2 activator[1][2].
CAS Number
64224-21-1
Product Name Alternative
RP 35972 (GMP) ; NSC 347901 (GMP)
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase; HIV; Keap1-Nrf2; Parasite
Type
GMP Small Molecules
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oltipraz-gmp.html
Smiles
S=C1SSC(C2=NC=CN=C2)=C1C
Molecular Formula
C8H6N2S3
Molecular Weight
226.34
References & Citations
[1]Lee WH, et al. Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect. Mol Cancer Ther. 2009 Oct;8 (10) :2791-802.|[2]Eba S, et al.The nuclear factor erythroid 2-related factor 2 activator oltipraz attenuates chronic hypoxia-induced cardiopulmonary alterations in mice.Am J Respir Cell Mol Biol. 2013 Aug;49 (2) :324-33.
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported

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