TTNPB (GMP)

• Description :

  TTNPB (Ro 13-7410) (GMP) is TTNPB (HY-15682) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. TTNPB is a highly potent retinoic acid receptor (RAR) agonist[1][2].

• Product Name Alternative :

  Ro 13-7410 (GMP) ; Arotinoid acid (GMP) ; AGN191183 (GMP)

• UNSPSC :

  12352005

• Hazard Statement :

  H315-H319-H335-H360

• Target :

  RAR/RXR

• Type :

  GMP Small Molecules

• Related Pathways :

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/ttnpb-gmp.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)C1=CC=C(/C=C(C2=CC=C3C(C)(C)CCC(C)(C)C3=C2)\C)C=C1

• Molecular Formula :

  C24H28O2

• Molecular Weight :

  348.48

• Precautions :

  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

• References & Citations :

  [1]Pignatello MA, et al. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410) : binding affinities and disposition. Toxicol Appl Pharmacol. 1997 Feb;142 (2) :319-27.|[2]Manabu Kawata, et al. Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds. Stem Cell Reports. 2019 Sep 10;13 (3) :530-544.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  GMP Small Molecules

• Clinical Information :

  No Development Reported

• CAS Number :

  [71441-28-6]