TTNPB (GMP)

CAT: 0804-HY-15682G-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-15682G-01Size:10 mg
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Description
TTNPB (Ro 13-7410) (GMP) is TTNPB (HY-15682) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. TTNPB is a highly potent retinoic acid receptor (RAR) agonist[1][2].
CAS Number
[71441-28-6]
Product Name Alternative
Ro 13-7410 (GMP) ; Arotinoid acid (GMP) ; AGN191183 (GMP)
UNSPSC
12352005
Hazard Statement
H315-H319-H335-H360
Target
RAR/RXR
Type
GMP Small Molecules
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ttnpb-gmp.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C1=CC=C(/C=C(C2=CC=C3C(C)(C)CCC(C)(C)C3=C2)\C)C=C1
Molecular Formula
C24H28O2
Molecular Weight
348.48
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
[1]Pignatello MA, et al. Multiple factors contribute to the toxicity of the aromatic retinoid, TTNPB (Ro 13-7410) : binding affinities and disposition. Toxicol Appl Pharmacol. 1997 Feb;142 (2) :319-27.|[2]Manabu Kawata, et al. Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds. Stem Cell Reports. 2019 Sep 10;13 (3) :530-544.
Shipping Conditions
Room temperature
Scientific Category
GMP Small Molecules
Clinical Information
No Development Reported

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