BigLEN (rat) (TFA)

• Description:

  BigLEN (rat) is a potent GPR171 agonist with an EC50 of 1.6 nM[1].

• UNSPSC:

  12352209

• Target:

  GPR171

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/biglen-rat-tfa.html

• Solubility:

  H2O

• Smiles:

  O=C(N1[C@@H](CCC1)C(O)=O)[C@H]2N(CCC2)C([C@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H]3N(CCC3)C([C@H](C)NC([C@H](CCC(N)=O)NC([C@H]4N(CCC4)C([C@H](CO)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CCC(O)=O)NC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.O=C(C(F)(F)F)O

• Molecular Formula:

  C78H129F3N24O25

• Molecular Weight:

  1860.00

• References & Citations:

  [1]Gomes I, et al. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc Natl Acad Sci U S A. 2013;110 (40) :16211-16216.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported