TAT-cyclo-CLLFVY

CAT: 0931-TP2046Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-TP2046Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1446322-66-2

Target

HIF/HIF Prolyl-Hydroxylase

Related Pathways

Chromatin/Epigenetic, Metabolism

Bioactivity

Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50 = 1.3 μM) . Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cancer cells in vitro. Also reduces tubularization of hypoxic HUVECs.

Smiles

C(=O)([C@H]1N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CSSC[C@@H]2NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H]([C@@H](C)C)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC2=O)N)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CCC1)N5[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CCC5

Molecular Formula

C111H188N42O24S2

Molecular Weight

2559.1

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
TP2717-01	Cyclo (CLLFVY)
TP1809-01	TAT
TP3513-01	Cyclo (CRLLIF)
TP1330-01	Cyclo (RADfK)
T82641-01	Cyclo (RGDyC)
T131009-01	Cyclo (phenylalanyltryptophyl)
T72905-01	Cyclo (RLsKDK)
T6812-01	Cyclo (-RGDfK)
T31133-01	Cyclo-cadagac
T130102-01	Cyclo (isoleucylprolyl)

Alternative Products

Catalog	Name
MBS5764041	TAT-cyclo-CLLFVY
MBS5817847	TAT-cyclo-CLLFVY TFA
A22796-10	TAT-cyclo-CLLFVY 10mg
A22796-5	TAT-cyclo-CLLFVY 5mg
HY-P1420A	TAT-cyclo-CLLFVY (TFA)
A22796-1	TAT-cyclo-CLLFVY 1mg
CRB1001365-01	Cyclo (CLLFVY)
CRB1001365-01	Cyclo (CLLFVY) - (Cancer Peptides)
MBS406125-01	cyclo
068-27	TAT Derivative, R9-Tat

TAT-cyclo-CLLFVY

Related Products

Alternative Products

Popular Products