Parstatin (human)

• Target:

  Protease-activated Receptor

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  Cell-permeable peptide cleaved from protease-activated receptor 1 (PAR1) upon receptor activation. Attenuates endothelial cell migration and proliferation (IC50 ~ 3 ?M), and induces cell cycle arrest. Promotes activation of caspase-3 and exhibits pro-apoptotic activity in vitro. Inhibits angiogenesis and exhibits cardioprotective activity in vivo.

• Molecular Formula:

  C191H330N64O53S3

• Molecular Weight:

  4467.29

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1065755-99-8