Parstatin(mouse) (TFA)

• UNSPSC Description:

  Parstatin(mouse) TFA, a cell-penetrating PAR-1 thrombin receptor agonist peptide, is a potent inhibitor of angiogenesis[1][2].

• Target Antigen:

  Protease Activated Receptor (PAR)

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/parstatin-mouse-tfa.html

• Purity:

  99.71

• Solubility:

  H2O : 100 mg/mL (ultrasonic)

• Smiles:

  OC(C(F)(F)F)=O.O=C([C@@H](N)CCSC)NCC(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N5[C@H](C(N[C@H](C(O)=O)CCCNC(N)=N)=O)CCC5)=O)CC(N)=O)=O)C(C)C)=O)[C@@H](C)O)=O)C)=O)CC(O)=O)=O)[C@@H](C)O)=O)CCCNC(N)=N)=O)CCC(O)=O)=O)CO)=O)CCC(O)=O)=O)CCC4)=O)CCC(N)=O)=O)CO)=O)CCSC)=O)CCC3)=O)C(C)C)=O)CCCNC(N)=N)=O)CO)=O)CO)=O)CC(C)C)=O)CC(C)C)=O)CCC2)=O)=O)CS)=O)CC(C)C)=O)CO)=O)CC(C)C)=O)=O)CC(C)C)=O)C)=O)C(C)C)=O)[C@H](CC)C)=O)CC(C)C)=O)CC(C)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC1)=O

• Molecular Weight:

  4533.18

• References & Citations:

  [1]Panagiota Zania, et al. Parstatin, the Cleaved Peptide on Proteinase-Activated Receptor 1 Activation, Is a Potent Inhibitor of Angiogenesis. J Pharmacol Exp Ther. 2009 Feb;328(2):378-89.|[2]Jennifer L Strande, et al. Parstatin: A Cryptic Peptide Involved in Cardioprotection After Ischaemia and Reperfusion Injury. Cardiovasc Res. 2009 Jul 15;83(2):325-34.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

• Clinical Information:

  No Development Reported