RO-0335

• Target:

  Reverse Transcriptase

• Related Pathways:

  Microbiology/Virology

• Purity:

  0.9953

• Bioactivity:

  RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates.

• Smiles:

  NS(=O)(=O)c1ccc(NC(=O)Cc2ccc(Br)c(Oc3cc(Cl)cc(c3)C#N)c2F)c(Cl)c1

• Molecular Formula:

  C21H13BrCl2FN3O4S

• Molecular Weight:

  573.22

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  867365-76-2