Cbl-b-IN-2

• CAS Number :

  2503325-21-9

• Target :

  Others|||E3 Ligase Ligand-Linker Conjugate

• Related Pathways :

  PROTAC|||Others

• Bioactivity :

  Cbl-b-IN-2 is an orally active biological compound that inhibits the E3 enzyme Casitas b lineage lymphoma proto-oncogene b (Cbl-b) in the ubiquitin proteasome pathway and can be used in the study of diseases that modulate the immune system and are susceptible to regulation by the immune system. Cbl-b-IN-2 can also be used in cancer research alone or in combination with one or more immune checkpoint inhibitors, antitumour agents and radiopharmaceuticals.

• Smiles :

  C(C1(COC1)C2=CC(=CC=C2)N3CC=4C(C3=O)=CC(CN5C[C@@H](C)C(F)(F)CC5)=CC4C(F)(F)F)C=6N(C)C=NN6

• Molecular Formula :

  C29H30F5N5O2

• Molecular Weight :

  575.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C