Multi-kinase-IN-2

• Target:

  Others|||Apoptosis|||FGFR|||VEGFR|||Akt|||PDGFR|||c-Kit|||Src

• Related Pathways:

  Apoptosis|||Angiogenesis|||Others|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling

• Bioactivity:

  Multi-kinase-IN-2 is an orally active inhibitor of angiokinases. multi-kinase-IN-2 significantly inhibits the activity of angiokinases such as VEGFR-1/2/3, PDGFR?/?, FGFR-1, LYN and c-KIT kinases. -IN-2 significantly attenuates phosphorylation of AKT and ERK proteins, induces apoptosis and has anticancer effects.

• Smiles:

  C(\NC1=CC=C(C=C1)N2C(CN3CCN(C)CC3)=CC=C2C)(=C\4/C=5C(NC4=O)=CC(C(OC)=O)=CC5)/C6=CC=CC=C6

• Molecular Formula:

  C34H35N5O3

• Molecular Weight:

  561.67

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2095628-21-8