SOS1-IN-14

CAT: 0931-T63887-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T63887-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2793405-20-4

Target

Ras, Others, Kras

Related Pathways

MAPK, GPCR/G Protein, Others

Bioactivity

SOS1-IN-14 is a selective, potent, orally active SOS1 inhibitor (IC50: 3.9 nM) . sOS1-IN-14 is absorbed in the intestine using a P-glycoprotein-mediated efflux mechanism. sOS1-IN-14 can be used in the study of KRAS mutated cancers and is more effective in tumour suppression than BI-3406.

Smiles

[H][C@]12CN(CCN1c1cc3c(N[C@H](C)c4cccc(C(F)F)c4F)nc(C)nc3cc1OCC2)C(=O)C1(CC1)C#N

Molecular Formula

C29H29F3N6O2

Molecular Weight

550.57

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
BA5792-5.1	SOS1-IN-14
MBS128751-01	SOS1
BA5802-10	SOS1-IN-11
BA5788-10	SOS1-IN-15
10R-8598	SOS1 antibody
HY-144207	SOS1-IN-9
HY-145046	SOS1-IN-3
HY-176170	SOS1-IN-19
HY-175560	SOS1-IN-22
HY-144211	SOS1-IN-7

SOS1-IN-14

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