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BChE-IN-8

CAT: 0931-T62504-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62504-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2653349-78-9
Target
Beta Amyloid, Others
Related Pathways
Neuroscience, Others
Bioactivity
BChE-IN-8 (compound 20) is an orally active butyrylcholinesterase (BChE) inhibitor that crosses the blood-brain barrier, targeting eqBChE (IC50: 0.15 nM) and hBChE (IC50: 45.2 nM) . It is used in Alzheimer's disease (AD) research for its neuroprotective and cognitive improvement effects, affecting the cholinergic system, Aβ aggregation, and neuropeptide levels.
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C(C(NC1=CC(C#N)=CC(Br)=C1)=O)N2C(=NC=3C2=CC=CC3)C=4C(N)=NON4
Molecular Formula
C18H12BrN7O2
Molecular Weight
438.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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