BChE-IN-8

• Target:

  Beta Amyloid|||Others

• Related Pathways:

  Neuroscience|||Others

• Bioactivity:

  BChE-IN-8 (compound 20) is an orally active butyrylcholinesterase (BChE) inhibitor that crosses the blood-brain barrier, targeting eqBChE (IC50: 0.15 nM) and hBChE (IC50: 45.2 nM) . It is used in Alzheimer's disease (AD) research for its neuroprotective and cognitive improvement effects, affecting the cholinergic system, A? aggregation, and neuropeptide levels.

• Smiles:

  C (C (NC1=CC (C#N) =CC (Br) =C1) =O) N2C (=NC=3C2=CC=CC3) C=4C (N) =NON4

• Molecular Formula:

  C18H12BrN7O2

• Molecular Weight:

  438.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2653349-78-9